For a medical emergency call 999. For urgent but non-emergency medical help call NHS 111.

Pain relief

For most everyday pain, paracetamol and ibuprofen are the two safest and most effective over-the-counter options in the UK. They work in different ways and can, for most people, be taken together for severe pain. A pharmacist can tell you which is best for you.

Looking after yourself

  • Paracetamol (adults): 500mg to 1g up to four times a day, at least four hours apart. Do not exceed 4g in 24 hours
  • Ibuprofen (adults): 200mg to 400mg up to three times a day with food. Avoid if you have asthma, stomach ulcers, kidney problems, or if you are pregnant (especially third trimester) — ask a pharmacist
  • Children: follow the dose on the bottle for their age; do not give aspirin under 16
  • Check other cold, flu or pain remedies to avoid a double dose

When to get medical help

Use NHS 111 online, call 111, or contact your GP if:

  • Pain is not controlled after 48 hours of over-the-counter pain relief
  • You are on other medicines and unsure what is safe to combine
  • You need pain relief on most days

Further information

This page provides general information only. It is not a diagnosis and is not a substitute for professional medical advice.